News & Latest Findings

Enrollee contributions are resulting in the latest published research in top journals. Below are some of the articles published from our findings.

Updated data through 10/31/2020.

aed-scroll-2

Get our latest study developments straight to your inbox.

Press Releases & News Coverage

21 March 2005
American Academy of Neurology
Press Release
Click here for full text

22 March 2005
Anti-Seizure Drug Valproate Linked to Birth Defects
Daily News Central – Media Coverage
Click here for full text

Journal Articles

Toufaily, M. H., Westgate, M.-N., Lin, A. E., Holmes, L. B.
Causes of Congenital Malformations
Birth Defects Research
2018; 1 10:87-91
Click here for full text

Holmes, L. B.
Commentary: Setting Standards for Pregnancy Registries
Drug Safety
2018; 41:7-9
Click here for full text

Hernández-Diaz, S., McElrath, T. F., Glynn, R. J., Pennell, P. B., Hauser, W. A., Yerby, M., Holmes, L. B.
Fetal Growth and Premature Delivery in Pregnant Women on Anti-epileptic Drugs
Annals of Neurology
Accepted Article, doi: 10.1002/ana.25031
Click here for full text

Margulis, A.V., Mittleman, M.A., Glynn, R. J., Holmes, L. B., Hernandez-Diaz, S.
Effects of Gestational Age at Enrollment in Pregnancy Exposure Registries
Pharmacoepidemiology and Drug Safety
2015; 24:343-352
Click here for full text

Herndandez-Diaz, S., Mittendorf, R., Smith, C.R., Hauser, W.A., Yerby, M., Holmes L.B.
Association Between Topiramate and Zonisamide Use During Pregnancy and Low Birth Weight
Obstetrics & Gynecology
2014; 123(1):21-28
Click here for full text

Herndandez-Diaz, S., Smith, C.R., Shen, A., Mittendorf, R., Hauser, W.A., Yerby, M., Holmes L.B.
Comparative Safety of Antiepileptic Drugs During Pregnancy
Neurology
2012; 78:1692-1699
Click here for full text

Holmes, L. B., Westgate, M.N.
Using ICD-9 Codes to Establish Prevalence of Malformations in Newborn Infants
Birth Defects Research (Part A): Clinical and Molecular Teratology
2012; 94:208-214
Click here for full text

Holmes, L. B., Westgate, M.N.
Inclusion and Exclusion Criteria for Malformations in Newborn Infants Exposed to Potential Teratogens
Birth Defects Research (Part A): Clinical and Molecular Teratology
2011; 91:807-812
Click here for full text

Holmes L.B., Wyszynski D.F., Baldwin, E.J., Smith, C.R., Habecker, E., Glassman, L.H.
Increased Frequency for Isolated Cleft Palate Among Infants Exposed to Lamotrigine During Pregnancy
Neurology 2008; 70:2152-2158
Click here for full text

Bromfield, E. B., Dworetzky, B. A., Wyszynski, D. F., Smith, C.R., Baldwin, E. J., Holmes, L. B.
Valproate Teratogenicity and Epilepsy Syndrome
Epilepsia 2008; 49(12):2122-2124
Click here for full text

Wyszynksi D.F., Nambisan M., Surve T., Alsdorf R.M., Smith C.R., Holmes L.B.
Increased Rate of Major Malformations in Offspring Exposed to Valproate During Pregnancy
Neurology 2005; 64:961-965
Click here for full text

Holmes L.B., Wyszynski D.F.
North American Antiepileptic Drug Pregnancy Registry
Epilepsia 2004; 45(11):1465
Click here for full text

Holmes L.B., Wyszynski D.F., Lieberman E.S.
The AED (Antiepileptic Drug) Pregnancy Registry: A 6-Year Experience
Arch Neurol. 2004; 61:673-678
Click here for full text

Abstracts & Other Texts

Smith, C.R., Holmes, L.B.
Recruitment of An Unexposed Control Group For A Pregnancy Registry
Birth Defects Research (Part A) 82:311 (2008)
Click here for full text

Holmes, L.B., Smith, C.R., Herndandez-Diaz, S.
Pregnancy Registries: Larger Sample Sizes Essential
Birth Defects Research (Part A) 82:307 (2008)
Click here for full text

A North American Registry for Epilepsy and Pregnancy, a Unique Public/Private Partnership of Health Surveillance
Epilepsia 1998;39:793-798
Click here for full text